Western blotting

Abzyme Therapeutics is a biopharmaceutical discovery and service company located outside Philadelphia, specializing in modular antibody discovery and conditionally-active antibody engineering for immunotherapy using proprietary antibody generation and optimization platforms based on yeast-display, self-diversifying libraries and FACS single-cell sorting. The company has over 60 therapeutic and diagnostic assets in development for infectious diseases, cancer, ophthalmology, inflammation and central nervous system disorders.

affinity maturationantibody discoveryantibody humanizationantibody optimizationbispecific antibody generationELISAFACS single-cell sortingFlow Cytometryimmunohistochemistryllama immunizationsurface plasmon resonanceyeast display

Blotting Innovations develops high-throughput western blotting products, including the G-Blot system, which allows running up to 96 samples in a single gel instead of 10 gels. The company has roots in academic research and aims to give scientists affordable tools that maximize productivity and reproducibility for protein analysis.

custom gel acrylamide concentrationselectrophoresisprecast gel manufacturingsemi-dry protein transfer

ITSI-Biosciences (ITSIBIO) is a life science contract research organization based in Johnstown, Pennsylvania, providing genomics, proteomics, and mass spectrometry services and developing ready-to-use kits for biomedical research. It serves universities, biotechnology and pharmaceutical companies, government agencies, and private industry clients locally, nationally, and internationally.

2D-DIGE2D-PAGEautoantibody detectionDNA analysisLC-MS/MSmass spectrometryprotein fractionation and enrichmentprotein isolationproteomicsquantitative multiplexed protein analysisquantitative multiplexed RNA analysis