antibody optimization

Abwiz Bio is a fee-for-service antibody lab founded in 2012 with a PhD-led scientific team. It specializes in antibody engineering, including STEM™ staged affinity maturation and RabWiz™ rabbit immunization paired with phage display, plus antibody humanization and optimization. The company holds a patented WizAmp™ library construction method (US Pat. 9,890,414) and sells recombinant rabbit monoclonal antibodies, phospho antibodies, cell surface antibodies, and SARS-CoV-2 antibodies and proteins.

affinity maturationantibody engineeringantibody humanizationcell-based phage display panninglibrary constructionphage displayrabbit immunization

Abzyme Therapeutics is a biopharmaceutical discovery and service company located outside Philadelphia, specializing in modular antibody discovery and conditionally-active antibody engineering for immunotherapy using proprietary antibody generation and optimization platforms based on yeast-display, self-diversifying libraries and FACS single-cell sorting. The company has over 60 therapeutic and diagnostic assets in development for infectious diseases, cancer, ophthalmology, inflammation and central nervous system disorders.

affinity maturationantibody discoveryantibody humanizationbispecific antibody generationELISAFACS single-cell sortingFlow Cytometryimmunohistochemistryllama immunizationsurface plasmon resonanceWestern blottingyeast display

IDBiologics was founded to discover and develop human monoclonal antibodies (mAbs) for the prevention and treatment of infectious diseases. Founded from the laboratory of Professor James Crowe at Vanderbilt University Medical Center (VUMC), its fully human mAb platform enables rapid discovery and optimization of broad and potent therapeutic mAbs with neutralizing activity to a range of viral targets. The company is based in Nashville, Tennessee.

human monoclonal antibody discoverytherapeutic antibody development