ELISA

Abzyme Therapeutics is a biopharmaceutical discovery and service company located outside Philadelphia, specializing in modular antibody discovery and conditionally-active antibody engineering for immunotherapy using proprietary antibody generation and optimization platforms based on yeast-display, self-diversifying libraries and FACS single-cell sorting. The company has over 60 therapeutic and diagnostic assets in development for infectious diseases, cancer, ophthalmology, inflammation and central nervous system disorders.

affinity maturationantibody discoveryantibody humanizationantibody optimizationbispecific antibody generationFACS single-cell sortingFlow Cytometryimmunohistochemistryllama immunizationsurface plasmon resonanceWestern blottingyeast display

Affinity Molecules offers custom cell line generation services spanning expression construct generation to manufacturing-grade, GMP-amenable CHO-based cell lines for antibody and biologic production. It also provides protein and antibody production and purification services, customized biological assay development, and mycoplasma detection services. The team was awarded an NIH Phase I grant for large scale in vitro production of capped polyadenylated mRNA-based vaccines.

antibody productionantibody purificationbacterial expression systemscell-based assayscell line generationFlow Cytometrygene synthesisinducible expressioninsect expression systemsmammalian expression systemsPCR-based mycoplasma detectionplasmon resonanceprotein characterizationprotein productionprotein purificationstable expressiontransient expression

Agri-Analysis LLC is a plant diagnostic laboratory in Davis, California, operating since 1981. It provides grapevine virus and disease testing, seed testing, and plant pathogen testing using technologies such as polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA). The company offers a Vineguard Panel of assays and a Vineyard Virus Survey program, and is a member of the Napa Valley Grape Growers Association, the California Seed Association, and the American Phytopathological Society.

nucleic acid based assayPCR testingseed testingvineyard virus surveyvirus and pathogen detection

Ansh Labs is a developer and manufacturer of immunoassay reagent test kits used to advance target discovery, therapeutic development, biomedical research, and clinical diagnostics. The company serves life science researchers, physician researchers, hospitals, commercial laboratories, and public health agencies, and its products support research in reproductive function, pregnancy, central nervous system, atherosclerotic cardiovascular disease, and oncology. Ansh Labs is now part of the VION Biosciences family of companies.

antibody development and screeningassay developmentassay optimizationassay validationCLIAimmunoassay developmentimmunofluorescenceimmunohistochemistryluminogenic microplatemonoclonal antibody developmentneutralizing antibodyWestern blot

Arbor Assays is a proudly employee-owned company based in Ann Arbor, Michigan, dedicated to delivering high-quality detection and immunoassay kits. On January 1, 2017, it became the world's first employee-owned life sciences company through a perpetual employee benefit trust (EBT). It builds high-quality detection and immunoassay kits known for sensitivity, speed, and convenience, using top-tier suppliers and referencing WHO or NIST standards.

chemiluminescent ELISAcolorimetric detectionimmunoassaysample testing services

AVS Bio is a USDA-licensed biologics manufacturer and supplier of avian biological materials and antibody discovery services for biopharmaceutical companies, diagnostic developers, and research institutions. Since 1961, it has provided SPF eggs, antigens, recombinant proteins, custom antibodies, and primary chicken cell products, supporting vaccines, therapeutics, diagnostics, and environmental testing worldwide.

9 CFR testingagar gel precipitin testsantibody developmentantibody discoverycustom assay developmenthemagglutination inhibition assaysIgY antibody productionindirect fluorescent antibody testingmicroneutralization testsPCR testingserum neutralization testsserum plate agglutinationvirus production

Avrok Biosciences is an integrated specialty laboratory and contract research organization (CRO) that delivers complete biospecimen services under one roof, including procurement, processing, testing, bioinformatics, and biostorage. The company supports drug development, diagnostics, clinical studies, and translational research, and through its Beyond the Bench Initiative donates a portion of proceeds from every completed project to a nonprofit in the same therapeutic area.

ABO typingGC/MS/MSHLA typingLC/MS/MSMicroarraynext-generation sequencingPBMC/plasma/serum isolationPCR and qPCRwhole exome sequencingwhole genome sequencing

Beacon Scientific is a lateral flow CDMO (Contract Development and Manufacturing Organization) specializing in lateral flow development and the creation of lateral flow assays (LFAs) for rapid, reliable, and cost-effective diagnostic solutions. The company offers IVD rapid prototyping, product development, and manufacturing, with decades of experience developing and commercializing medical devices. It operates under an ISO 13485:2016 Quality Management System and has developed products in oncology, veterinary medicine, chronic disease, infectious disease

3PL planningbiobankingbiomarker discovery and validationcassette engineeringcell culturingconjugation scale-upcustom surface chemistryIVD manufacturingIVD product developmentIVD rapid prototypinglateral flow assay developmentlateral flow developmentLuminexlyophilizing reagentsMSDproject managementQMS integrationreagent formulationtech transfer management

Biomerica is a global biomedical technology company that develops, patents, manufactures and markets advanced in-vitro diagnostic and therapeutic products. Its primary research and development focus is on gastrointestinal and inflammatory diseases, and its diagnostics are used worldwide for screening and detection of high-prevalence chronic medical conditions. The company operates FDA and CE registered manufacturing facilities in Irvine, California and Mexicali, Mexico, and is a contract manufacturer for multinational pharma companies and other diagnosti

at-home testingcontract manufacturingFDA and CE registered manufacturingin vitro diagnostics manufacturingpoint of care testingrapid testsresearch and development

BioModels is a Boston-based preclinical contract research organization (CRO) that specializes in the development and execution of efficacy studies in mouse and rat disease models. It provides preclinical animal models and clinically relevant disease models to evaluate novel therapeutics, offering a start-to-finish solution from initial inquiry to study execution and data delivery.

blood/sample analysiscellular and molecular characterizationFlow Cytometrygene expression analysishistopathologyin-life monitoringin vitro and ex vivo assaysmicrobiology and microbiomemultiplex cytokine analysisqPCRRNA/DNA isolationsurgerytissue and sample processing

BIOQUAL is a specialist preclinical contract research organization (CRO) founded in 1981, providing comprehensive in vivo and in vitro preclinical research services to pharmaceutical, biotechnology, government, and academic organizations. The company focuses on infectious and human diseases, including virology, bacteriology, and parasitology, and also applies its capabilities to oncology and immunogenicity studies. Its labs operate up to Select Agent/BSL-3 standards and it is AAALAC-accredited.

BSL3 facilitiescell-based assayscustom animal model developmentcustom assay developmentcytotoxicity testingELISpotFlow CytometryGLP servicesimagingimmunoassaysIND-enabling servicesin vitro researchin vivo researchLuminexpharmacokineticsPRNT and microneutralization assaystoxicology testingviral load assaysWestern blot

BioStone is a U.S.-based biotechnology company delivering integrated solutions in animal health diagnostics and management, food and feed safety, and USDA-licensed veterinary vaccine manufacturing. It owns and operates a 16,300-square-foot USDA-licensed facility (Est. 315) in Grand Prairie, Texas, acquired from American Animal Health, continuing autogenous bacterin manufacturing dating back to 1983. It supports veterinarians, producers, laboratories, and food and agricultural organizations through global subsidiaries and partnerships.

assay evaluationautogenous bacterin manufacturingcollaborative researchdiagnostic kit developmentimmunoassay productionlaboratory testingmolecular assay productionPCRUSDA-licensed veterinary vaccine manufacturingvaccine titer studies

Bio-Val Consulting, LLC (BVC) is a woman-owned small business founded in 2013 by CEO Kristin H. Clement, Ph.D., dedicated to helping clients navigate assay development and validation and meet regulatory compliance for bioanalytical needs. It offers consulting on quantitative MOA-based bioassays supporting drug research and development, including antibody screening, characterization, potency and stability testing.

antibody purificationassay developmentassay validationbinding assayscAMP stimulation assayscell-based assaysddPCRECL (Meso Scale Discovery)ELISpotFlow Cytometrylateral flow assay developmentneutralization assaysPCRphagocytosis assaysqPCRSDS-PAGE/Western Blot

specialize in the generation of custom antibodies and nanobodies for the scientific research, therapeutic, pharmaceutical, and diagnostic industries.

antibody production in alpaca, llama, rabbit, goat, and sheepconjugationcustom antibody generationnanobody generationPBMC isolationpeptide designpurification method developmentRNA purification

Comparative Biosciences, Inc. (CBI) was founded in 1996 to provide preclinical toxicology, pharmacokinetics, efficacy, pharmacology, and histopathology services to the biomedical and biopharmaceutical community. CBI is AAALAC accredited and registered with the FDA, USDA and OLAW, and operates a purpose-built facility in Sunnyvale, California with an in-house histopathology laboratory and full-time quality assurance unit.

CT scanningdigital radiographyhistopathologyimmunohistochemistryin situ hybridizationlaser DopplerMRIoptical coherence tomographyPCRpharmacokineticspreclinical toxicologyqPCRultrasound

Crystal Chem, established in 1989, specializes in providing high quality research kits to the scientific community. The company offers ELISA kits and assays for diabetes, obesity, food allergen detection, toxicology, endocrinology, cardiovascular disease, host cell proteins, immunology, and oxidative stress research. Its products have been cited in thousands of scientific publications, and it serves customers globally in the USA, Europe, Canada, and Asia.

lateral flow assayslyophilization service

Euroimmun US is a manufacturer and subsidiary of EUROIMMUN, described as a global leader in medical diagnostics innovating in autoimmune and infectious disease testing and beyond. The company offers diagnostic products across autoimmunity, infection, allergy, endocrinology, bone metabolism, neurodegeneration, therapeutic drug monitoring, human genetics, and tuberculosis, along with automation and software solutions.

ChLIAIFAImmunoblotMicroarrayMolecular genetic testingRadioimmunoassaysReal-time PCR

A small one-man laboratory continuing the themes of Fuller Laboratories, which was sold to VMRD after 35 years of diagnostic work with vector-borne agents. The lab operates a small Class 2 facility focused on cell culture and microscopy, and uses IFA, ELISA and western immuno-blot techniques. Its initial vaccine focus uses common but non-pathogenic Rickettsia spp. to attempt immunization against all species, and it collaborates with university research laboratories for agents such as Babesia microti and Theileria orientalis Ikeda.

cell cultureIFAMicroscopyvaccine researchwestern immuno-blot