cell-based assays

Affinity Molecules offers custom cell line generation services spanning expression construct generation to manufacturing-grade, GMP-amenable CHO-based cell lines for antibody and biologic production. It also provides protein and antibody production and purification services, customized biological assay development, and mycoplasma detection services. The team was awarded an NIH Phase I grant for large scale in vitro production of capped polyadenylated mRNA-based vaccines.

antibody productionantibody purificationbacterial expression systemscell line generationELISAflow cytometrygene synthesisinducible expressioninsect expression systemsmammalian expression systemsPCR-based mycoplasma detectionplasmon resonanceprotein characterizationprotein productionprotein purificationstable expressiontransient expression

Amerigo Scientific integrates global cutting-edge product and technical resources to provide the biomedical and life science research communities with high-quality antibodies, kits, proteins, and other products, along with technical equipment, instruments, and custom services for research institutions and enterprises in the biological, chemical, pharmaceutical, and medical industries.

3D tissue engineeringassay developmentbiomarker servicescalibration servicescell-free membrane protein expressionCRISPR sgRNA librariescustom probes for qPCRimmunotoxicity testingoligo synthesissolid-phase peptide synthesis

Amsbio is a leading provider of quality life science research reagents and services for customers developing innovative methods, processes, products and medicines. The company supplies antibodies, biospecimens, proteins, RNA, cells and cell culture products, kits and assays, molecular biology reagents, and custom services. It is an ISO 9001 registered firm.

CRISPR gene editingDrug screening serviceHistochemistryLentivirus & AAV packaging servicesmolecular biology servicesMonoclonal antibody servicepeptide synthesisPolyclonal antibody serviceProtein expression (bacterial, baculovirus, cell free, mammalian)Recombinant monoclonal antibody servicestem cell differentiationtissue procurement

Attana AB is a Swedish life science company that provides the life science community with analytical instruments and services for bioanalysis. Its proprietary biosensor technology measures molecular interactions in real time in biologically relevant environments such as blood, plasma, living cells and tissue, helping drug developers validate, select and optimize drug candidates for Phase I and Phase II studies. The company also offers contract research (CRO) services and diagnostics through Attana Diagnostics and Attana Virus Analytics (AVA).

antibody developmentbiosensor technologydrug discovery and developmentimmunogenicity studiesinteraction analysiskinetic analysislabel-free analysistranslational researchVaccine development

BioAgilytix is a global bioanalytical laboratory and contract QC laboratory providing pharmacokinetic (PK), immunogenicity, biomarker, and CMC analytical testing services in a GxP environment for pharmaceutical and biotechnology organizations throughout every phase of drug development. It maintains laboratories in Durham, North Carolina; Boston, Massachusetts; San Diego, California; Melbourne and Brisbane, Australia; and Hamburg, Germany.

assay development and validationflow cytometryGMP testingkit productionlab automation systemsLBA/immunoassaysmass spectrometrymethod transfermolecular assaysQC release and stability testingvirology

BIOQUAL is a specialist preclinical contract research organization (CRO) founded in 1981, providing comprehensive in vivo and in vitro preclinical research services to pharmaceutical, biotechnology, government, and academic organizations. The company focuses on infectious and human diseases, including virology, bacteriology, and parasitology, and also applies its capabilities to oncology and immunogenicity studies. Its labs operate up to Select Agent/BSL-3 standards and it is AAALAC-accredited.

BSL3 facilitiescustom animal model developmentcustom assay developmentcytotoxicity testingELISAELISpotflow cytometryGLP servicesimagingimmunoassaysIND-enabling servicesin vitro researchin vivo researchLuminexpharmacokineticsPRNT and microneutralization assaystoxicology testingviral load assaysWestern blot

Bio-Val Consulting, LLC (BVC) is a woman-owned small business founded in 2013 by CEO Kristin H. Clement, Ph.D., dedicated to helping clients navigate assay development and validation and meet regulatory compliance for bioanalytical needs. It offers consulting on quantitative MOA-based bioassays supporting drug research and development, including antibody screening, characterization, potency and stability testing.

antibody purificationassay developmentassay validationbinding assayscAMP stimulation assaysddPCRECL (Meso Scale Discovery)ELISAELISpotflow cytometrylateral flow assay developmentneutralization assaysPCRphagocytosis assaysqPCRSDS-PAGE/Western Blot

Burleson Research Technologies (BRT) is a contract research organization specializing in immune safety, immunotoxicology, and preclinical efficacy research for pharmaceutical, biotechnology, chemical, and medical device organizations. Founded in 1996 by Drs. Gary and Florence Burleson, BRT provides customized preclinical research programs integrating in vivo, in vitro, ex vivo, and bioanalytical capabilities. The company operates an approximately 10,000-square-foot facility in Morrisville, North Carolina, near Research Triangle Park.

bioanalytical assayscustomized study designex vivo assessmentshost resistance modelshumanized and immunocompromised mouse modelshypersensitivity modelsimmunogenicity testingimmunotoxicity testingin vitro assaysin vivo studiestumor models

Cells Online offers stable cell lines and primary cells for cell-based assays in drug discovery and biomedical research. Their stable cell lines include fluorescent cell lines, immortalized primary cells, knockout cell lines, immune and infectious research cell lines, CNS research cell lines, neurodegenerative disease model cell lines, GPCR cell lines, immune checkpoint cell lines, Fc Receptor cell lines, Claudin 18.2 cell lines, and apoptosis cell lines. Their primary cells include cardiac, dermal, endocrine, gastrointestinal, hepatic, neural, ocular, p

cell line developmentcloning & expressionCNS drug R&D servicesdrug screeningflow cytometry analysisfluorescent cell line developmentgene synthesisIF studyknockdown cell line developmentmammalian cell transfectionorgan-specific toxicity assaysphenotypic assaysplasmid constructionRT-PCRstable cell line development

Coho Biologics specializes in analytical testing solutions for the pharmaceutical, biotech, and life sciences industries, focusing on RNA and protein biological testing. The company provides rapid, affordable, and compliant results for testing proteins, RNA, and nanoparticle formulations, operating under FDA regulatory guidelines and adhering to cGMP and GLP standards. Services support vaccine and therapeutic development, preclinical testing, and cGMP quality control.

cGMP quality controlGLP testingimmunoassaysimpurity characterizationmethod developmentparticle sizingpotency assaysstability studies

Ealden Lab is a privately owned preclinical research services company founded in 2024 by scientists in Philadelphia, Pennsylvania, to help therapeutic startups fast-track discovery and preclinical research with minimal investment. It supports early-stage biotech and pharmaceutical clients worldwide with cell-based assays, target-specific assays, staining and imaging, tissue processing, and in vivo services.

automationdata analysis pipelineshigh-throughput drug screening assaysin vivo servicesquantitative imagingstable cell line generationstaining & imagingtarget-specific assaystissue processing

Eurofins DiscoverX is the products division of Eurofins Discovery and part of the Eurofins BioPharma global network. It provides cell-based assay products for drug discovery and development, used in screening and validation of therapeutic programs. Its portfolio includes ready-to-use homogeneous assay kits, stable engineered cell lines, membrane preps, recombinant proteins/enzymes, and qualified reagents.

assay kit developmentdrug discovery screening