affinity maturation

Abwiz Bio is a fee-for-service antibody lab founded in 2012 with a PhD-led scientific team. It specializes in antibody engineering, including STEM™ staged affinity maturation and RabWiz™ rabbit immunization paired with phage display, plus antibody humanization and optimization. The company holds a patented WizAmp™ library construction method (US Pat. 9,890,414) and sells recombinant rabbit monoclonal antibodies, phospho antibodies, cell surface antibodies, and SARS-CoV-2 antibodies and proteins.

antibody engineeringantibody humanizationantibody optimizationcell-based phage display panninglibrary constructionphage displayrabbit immunization

Abzyme Therapeutics is a biopharmaceutical discovery and service company located outside Philadelphia, specializing in modular antibody discovery and conditionally-active antibody engineering for immunotherapy using proprietary antibody generation and optimization platforms based on yeast-display, self-diversifying libraries and FACS single-cell sorting. The company has over 60 therapeutic and diagnostic assets in development for infectious diseases, cancer, ophthalmology, inflammation and central nervous system disorders.

antibody discoveryantibody humanizationantibody optimizationbispecific antibody generationELISAFACS single-cell sortingFlow Cytometryimmunohistochemistryllama immunizationsurface plasmon resonanceWestern blottingyeast display

Antibody Design Labs is a San Diego-based provider of phage display and antibody discovery products and services. With more than 30 years of experience, the company offers peptide and antibody phage display libraries, helper phages, phagemid and phage vectors, yeast display vectors, competent cells, and TGEX antibody expression vectors, along with services including peptide discovery, library construction, antibody discovery, engineering, reformatting, and expression.

antibody engineeringantibody humanizationantibody library constructionantibody reformattingimmunizationlibrary screeningmammalian cell expressionmolecular cloningpeptide library constructionphage displayphage display library constructiontransient antibody expressionyeast display

AvantGen is a San Diego-based biotechnology company that enables scientific partners in the discovery and optimization of novel antibody drugs. It uses a proprietary yeast display system and its Germliner™ Library Collection to provide fully human antibody platforms with more than 100 billion antibody clones, and offers affinity maturation and antibody engineering services.

antibody discoveryantibody engineeringbioconjugationcell sorting based screeninglibrary designQCrabbit monoclonal antibody generationrecombinant expression in HEK293 or CHO cellsyeast display