bioconjugation

Abzena is a fully integrated biologics and bioconjugates CDMO+CRO, founded in 2001, providing discovery through commercial services for antibodies, ADCs, AOCs, RDCs, vaccines, fusion proteins, bispecifics and other complex biologics. It operates integrated facilities in San Diego CA, Bristol PA, and Cambridge UK, with corporate headquarters in Raleigh, North Carolina, and has partnered with over 500 customers globally.

analytics and bioassaysantibody discoverycell line developmentcGMP manufacturingcomplex chemistryformulation developmentHPAPI handlingimmunogenicity testingprocess developmentprotein engineeringtechnology transfer

Antibody Solutions helps biopharmaceutical companies advance their discovery of better diagnostics and therapeutics by delivering fit-for-purpose antibodies. With more than 30 years of history, the company provides antibody discovery and production services under a fee-for-service, pay-as-you-go model that keeps client IP in their hands.

affinity purificationantibody discoveryantibody manufacturingantigen developmentassay developmentB-cell fusionFlow Cytometryhybridoma generationmolecular modelingmonoclonal antibody discoverypolyclonal antibody discoverysequencing

AvantGen is a San Diego-based biotechnology company that enables scientific partners in the discovery and optimization of novel antibody drugs. It uses a proprietary yeast display system and its Germliner™ Library Collection to provide fully human antibody platforms with more than 100 billion antibody clones, and offers affinity maturation and antibody engineering services.

affinity maturationantibody discoveryantibody engineeringcell sorting based screeninglibrary designQCrabbit monoclonal antibody generationrecombinant expression in HEK293 or CHO cellsyeast display

Azvlz Pharma is a supplier of high-quality chemical reagents and custom synthesis services for pharmaceutical and biotech research. It offers GalNAc derivatives, linkers, labeling reagents, and conjugation kits, along with custom synthesis, protein conjugation, and analytical services. The company states its products undergo HPLC and NMR verification and ships worldwide with cold-chain management.

ADC developmentcustom chemical synthesisHPLC analysisLC-MS analysisNMR spectroscopyPEGylationprotein conjugationsite-specific labelingstability testing

Bio-Synthesis is a U.S.-based custom synthesis and chemistry development CDMO supporting nucleic acids, peptides, bioconjugation, molecular biology services, analytical testing, scale-up, and therapeutic development workflows. Founded in 1984, it operates a 75,000 sq. ft. facility in Lewisville, Texas, with cGMP-aligned manufacturing from preclinical to commercial scale.

analytical testingcGMP manufacturingHPLC purificationmass spectrometry (MALDI-TOF, LC-MS, ESI)molecular biologyoligonucleotide synthesisPAGE purificationpeptide synthesisscale-up manufacturingtangential-flow filtrationUV spectrophotometry

CARBOGEN AMCIS is a Contract Development and Manufacturing Organization (CDMO) providing drug substance and drug product development, manufacturing, and commercialization services for the pharmaceutical and biopharmaceutical industries. It offers process development, scale-up, GMP API manufacturing, analytical services, stability studies, reference standards, and sterile drug product manufacturing, plus Cholesterol and Vitamin D specialties.

ADC manufacturinganalytical testingchromatographycrystallizationdrug product manufacturingflow chemistryGMP API manufacturinglyophilizationmicrobiology testingnon-GMP manufacturingprocess developmentreference standard characterizationScale upstability studiestech transfer

CellMosaic, Inc. is a bioconjugation company founded in 2008 and based in Woburn, Massachusetts. It develops proprietary AqueaTether® (AqT®) technologies and provides custom bioconjugation services, bioconjugate drug development and manufacturing, diagnostic conjugate development, and bioanalytical services including HPLC analysis, purification, and bioassays. It also sells bioconjugation kits and reagents for antibody, protein, peptide, oligonucleotide, and small molecule labeling.

ADC development and manufacturingantibody fragmentationantibody labelingbioassay servicesbioconjugate drug development and manufacturingbiotinylationcrosslinkingcustom synthesisfluorescent dye labelingHPLC analysispurification