medical device development

Cerulean Scientific develops clog, obstruction, and biofouling resistant medical devices, including products featuring Cerulean Surface technology and a Cerulean Hemodialysis Catheter. The company focuses on reinventing care for pediatric and adult hydrocephalus and improving vascular access for hemodialysis, partnering with clinicians and researchers at leading universities.

surface technology

CF Neuromedics, Inc. is a start-up company dedicated to revolutionizing the field of neurology. It develops next-generation device-based strategies integrating multi-modal neuromodulation techniques to treat neurological disorders, with primary emphasis on non-opioid alternatives for chronic pain, especially pain originating from deep tissues.

multi-modal neuromodulation

Chitogen Inc. is a medical device company dedicated to the development of next generation proprietary hemostatic products for the control of severe bleeding. Its SoftSeal-STF Hemostatic Pad utilizes chitosan fiber to accelerate the formation of a natural blood clot, and the Chitogen family of products is designed to supply lifesaving hemostasis for surgical, cardiovascular catheterization and dialysis environments.

development of hemostatic products

Choice is developing a hormone-free, reversible contraceptive valve implant placed in each fallopian tube in an outpatient procedure through the vagina and cervix. Closed, it is designed to keep sperm and egg apart; opened, it is designed to let fertility return. It is an investigational device, not approved or available in any market, designed and built in Eindhoven on the former Philips site under an ISO 13485 certified quality system.

fine mechanicsISO 13485 certified quality systemmedical regulation

ColoWrap is a medical device company that developed the ColoWrap Anti-Looping Abdominal Compression Device, a patented two-part system providing firm, sustained compression to prevent and resolve looping during colonoscopy. Founded by Dr. Marybeth Spanarkel and healthcare entrepreneur James Hathorn, the company aims to make colonoscopy safer for patients and healthcare providers by eliminating the need for manual pressure and patient repositioning.

AI data collection and analysis

CoolSpine LLC is an early stage medical device company spun out of Yale University developing neuroprotective medical devices that induce localized hypothermia to prevent spinal cord and brain injuries by reducing the consequences of spinal and cerebral ischemia. Its patented technology cools cerebral spinal fluid with a multi-lumen catheter through which cold saline is circulated in a closed loop, lowering spinal cord or brain temperature while the core body remains normothermic.

animal testingcerebral spinal fluid coolinglocalized therapeutic hypothermia

Coram Technologies is a startup founded and led by Dr. Henry Halperin to commercialize new medical devices, including CPR related technologies and new, interactive educational approaches such as video game based learning. The company focuses on medical device development and manufacturing.

medical device manufacturing

CranioSense, Inc. is a medical technology company based in Bedford, Massachusetts, developing IHdetect, a portable non-invasive system to help clinicians triage and monitor elevated intracranial pressure (ICP) earlier in the care journey without drilling a hole in the skull or inserting a sensor into the brain. The IPASS system measures ICP using a forehead patch, two clip-on sensors, and a handheld device the size of an iPad.

non-invasive intracranial pressure assessment

CX Therapeutics is a medical device company focused on developing an improved cerclage to treat cervical insufficiency and prevent preterm birth. Working with mechanical engineers and medical device experts, the company aims to make cerclage safer and more effective. Its work includes preclinical testing of a prototype medical device and benchtop testing of the Cx Device.

benchtop testingpreclinical testing

CytexOrtho is a clinical stage medical device company working to advance orthopaedic treatment options for cartilage repair, leveraging tissue regeneration work of Dr. Farshid Guilak, Dr. Bradley Estes, and Dr. Frank Moutos. Its lead product, the ReNew Hip implant, is an acellular implant to restore hip joint health in young patients, and is in an FDA-approved pilot clinical trial. The company is also testing its technology for other joints such as knees and shoulders.

cartilage repairclinical trialsmanufacturing processestissue regeneration

CytoAstra is developing the Cytophone platform, which uses In Vivo Photoacoustic Flow Cytometry (PAFC) for early diagnosis of life-threatening diseases including cancers, infections, and cardiovascular disorders, with a focus on melanoma, malaria, and strokes. The technology is noninvasive, label-free, and operates through intact skin using a laser and ultrasound transducers. CytoAstra is also developing a therapeutic device that can detect and treat cancer and infected cells using photoacoustic and photothermal technologies.

clinical trialsIn Vivo Photoacoustic Flow Cytometry (PAFC)photoacoustic detectionphotothermal technologies

DeGen Medical Inc. is a medical device development company focused on spinal care, developing world-class implants and intuitively designed instrumentation to treat complex spinal diseases. The company is patient-centric and aims to improve outcomes of spine surgery. It also offers DeGen Medical XR™, an AI-driven augmented reality platform for surgical and clinical settings, and additive manufacturing for patient-specific care.

3D Printed Solutionsadditive manufacturingAugmented Reality surgical platforms

Dilon Technologies Inc. is a medical device manufacturer based in Newport News, Virginia, that develops, manufactures, and promotes innovative medical devices for healthcare providers. It describes itself as a women's healthcare company that has expanded into biosurgery, with a mission to unite technology and talent to eradicate breast cancer. Its portfolio includes the Navigator System surgical gamma probe, MarginProbe for margin assessment in breast cancer surgery, and the CoPilot video laryngoscope.

medical device manufacturing

Dobli Engineering Services is a veteran owned and operated business serving contract needs. With combined experience in test fixture development, product development, requirements development, purchasing and procurement, and scoping third party certification requirements and testing, they provide the complete package. They are 100% committed to quality and strive to satisfy all customer requirements.

Electronic fabricationEmbedded designFixture design / replacementHardware assembliesindustrial engineeringMilitary and aerospace engineeringprototype developmentSoftware Design and DevelopmentSystem design and testingTechnical requirements development

DoubleLock Healthcare, Inc. is an early stage medical device company co-founded by Danny Wong, PharmD, and Elizabeth Wong, CRNA, MSN. It aims to be a world leader in asepsis innovation and Luer-lock misconnection prevention by revolutionizing the science of IV drug delivery. Its vision is for the Double-Lock Sterile Entry Intravenous Port and Syringe System to become the new standard-of-care in IV drug delivery. The company has joined GEDSA and AAMI.

asepsis innovationLuer-lock misconnection prevention

Dreamscape Medical is an innovative patient-focused medical device company dedicated to early detection of brain and sleep disorders. Since 2007, it has been inventing, developing and testing technologies to detect epileptic seizures, dementias, strokes, sleep apnea, and other brain-linked health problems. It develops advanced non-invasive medical devices for remotely monitoring brain and body health, protected by U.S. and international patents.

AI-assisted monitoringcloud data transmissionwearable microsensors

DynamicBio Technologies develops platforms for cell culture, disease modeling, and medical devices. Its products include SimpleSoft™, a flexible 2D substrate insert that converts rigid culture plates into softer tissue-like surfaces, SimpleSoft™ 3D acellular tissue scaffolds, and VascuCore™, a biomimetic vascular construct platform under development. The company aims to create physiologically relevant human tissue models to reduce reliance on animal testing and improve drug screening.

3D tissue scaffold engineeringbiomimetic vascular construct developmentcell culture platform developmentdisease modeling

EEA Innovations specializes in medical device development, delivering engineering, regulatory, testing, and commercialization services. With over two decades of experience, the team has developed 10+ FDA-cleared products and operates within a QMS aligned with ISO 13485 and IEC 62304, partnering with innovators to fast-track medical technologies, software, and devices from concept to commercialization.

3D printingbiological evaluation (ISO 10993)design for manufacturingdesign transferEMC safety testingmachiningmoldingpackaging designpackaging validationprocess validationQMS (ISO 13485)rapid prototypingregulatory strategyrisk management (ISO 14971)software development (IEC 62304)sterilization validationsupplier qualificationusability testing (IEC 62366)verification and validation

Electromed develops, manufactures, and markets innovative airway clearance devices, including the SmartVest Airway Clearance System, designed to provide symptom relief for people with chronic lung conditions such as bronchiectasis and COPD. The company is dedicated to high frequency chest wall oscillation (HFCWO) therapy, with 30 years of product development and customer support. Products are designed, engineered, and manufactured in Minnesota, United States.

engineeringHFCWO therapymanufacturing

Watch Video Launched 2022 NYSE stock symbol ENOV Team members 8,000+ Medical devices 1,000+ Facilities worldwide 30 Patents* 1,239 Creating the next generation of possible. Together. Enovis™ is a global medical technology innovator dedicated to improving lives by developing clinically differentiated solutions that enhance patient outcomes and restore motion for life. With thousands of employees worldwide and an extensive range of products, services, and integrated technologies, we strive to make each day better by partnering with the brightest minds to advance smarter, personalized, and more effective care that impacts patients wherever they are on their pathway to health. Explore our History Our culture of continuous improvement Continuous improvement is our core value and the foundation of everything we do. We know that the power to create better – for our customers, team members, and.

bracing design and manufacturingdistribution of orthopedic bracing and soft goodsorthopedic implant manufacturing

Empyrean Medical Systems is a Boca Raton, Florida company established in 2020 dedicated to transforming cancer treatment. Its expertise spans a research and clinical devices division and an informatics division, with additional therapeutics and informatics divisions, integrating quantum physics, molecular biology, chemistry, and machine learning to offer accuracy and safety in cancer treatment and research.

machine learningoncology researchparticle physics research

EndoSpace Corporation was founded by a New Jersey-based Gastroenterologist, a seasoned Financial Officer, and a Medical Sales & Marketing Professional. Since the three founders teamed up in 2012, they developed and brought to market SpaceBander, a medical device used by Gastroenterologists and Colorectal Surgeons to eliminate hemorrhoids. The company is committed to creating innovative and affordable solutions for Gastroenterologists, Colorectal Surgeons, and their patients while producing strong financial results for investors.

endoscopic product development

Enexor Health Systems designs, develops, and manufactures American-built medical equipment, including critical care respiratory devices. The company began as an emergency response, engineering emergency ventilators during the COVID-19 ventilator shortage, and received FDA Emergency Use Authorization for the VENT-LS critical care ventilator, which was placed in 27 U.S. hospitals. It is now designing the next generation of critical care respiratory devices.

medical device designmedical device manufacturing

Envision Research Inc is a clinical research organization whose mission is to advance medical research through innovative solutions and improve healthcare outcomes by developing groundbreaking therapies and technologies. Its team consists of experienced principal investigators and dedicated staff delivering patient-focused research across multiple therapeutic areas, partnering with sponsors and CROs to deliver efficient clinical trials.

clinical researchclinical trial recruitment and enrollmentdrug discoveryparticipant retentionregulatory and GCP compliance