upstream process development

Celltheon develops leading edge technologies and innovative solutions for the next generation of biotherapeutics. It offers platformed and custom end-to-end solutions for drug developability, cell line development, and process development to bridge the gap between early drug development and manufacturing. Located in the SF Bay Area, Celltheon has worked on 1000+ proteins for its 100+ global clients.

analytical characterizationbiochemical assay developmentbiological activity assay developmentcell line developmentchromatographydownstream process developmentGLP bioproduction and scale uppurificationstirred-tank bioreactor productiontech transfertox material productiontransient production

Curia is a global contract research, development and manufacturing organization (CDMO) with over 30 years of experience guiding clients through drug discovery, development, and manufacturing. It offers services across Small Molecule, Generic APIs, Sterile Drug Product, and Biologics, operating an integrated network of 20+ facilities and 3,000+ professionals across North America, Europe, and India.

analytical testingantibody discovery and engineeringchemical process R&Ddownstream process developmentdrug discoveryfermentationflow chemistryGMP manufacturinghigh potency API (HPAPI) manufacturingLNP formulationmammalian cell line developmentmRNA process developmentrecombinant antibody productionrecombinant protein productionsterile API manufacturing

CuriRx, Inc. is a pharmaceutical CRDMO based in Wilmington, Massachusetts, providing a broad range of services to pharmaceutical companies of all sizes. Its services include formulation, prefilled syringes, lyophilization, nanotechnology, advanced bioprocessing, cell line and strain development, upstream and downstream process development, and analytical services through its CuriLytics platform.

analytical method developmentbioprocessingcell line and strain developmentdownstream process developmentformulationhigh-resolution mass spectrometrylyophilizationnanotechnologyproteomicsqualification and validationstability testing