multi-objective optimization

Cortex Dynamix is dedicated to advancing the protection and prediction of traumatic brain injury (TBI) for the U.S. government and society. Leveraging expertise in experimentation, simulation, and the mechanics of brain injury, the company develops advanced materials and configurations to mitigate the risk of TBI from multiple threats, supporting safety improvements for military personnel, first responders, and athletes.

3D printingadditive manufacturingcomputational modelingexperimental instrumentationexperimentationexplicit finite element modelingimpact experimentationshock tube blast experimentssimulation

CuraGenAI designs disease-modifying small molecules for hard-to-treat diseases and accelerates target-to-lead discovery by combining generative AI, reinforcement learning, and ML model architectures with biology and structure-based validation. Its CureRX platform delivers synthesis-ready lead series to pharma and biotech partners, compressing target-to-lead discovery from years to weeks. Selected programs advance toward clinical translation through CuraGen Neuro Therapeutics, including a brain-directed ACAT1/SOAT1 program in glioblastoma.

ADMET predictionde novo molecular designgenerative chemistryReinforcement learningsmall-molecule discoverystructure-based validationtarget definition and druggability assessment

TRANSFORMING THE DRUG DISCOVERY PROCESS With our decades’ worth of drug discovery expertise and breakthrough computationalplatform, we are setting the pace for the next generation of drug discovery. No Guesses, Just Successes by Computational Design Learn More About Our Platform Denovicon’s mission is to bring better quality drugs to market faster and more affordably than existing methods. To do so, we’ve created a drug discovery platform that’s powered by AI, machine learning, generative therapeutic design, and physics-based approaches to achieve the best results. The platform effectively and swiftly triages trillions of molecules to identify high-quality leads (not simply hits) and transform them into optimized clinical candidates. In this way, the platform streamlines the overall drug discovery process leading to savings in time and money, while achieving higher rates of clinical.

AI/machine learning drug discoverycomputational designgenerative therapeutic designphysics-based modelingsmall molecule drug discovery

Evolved Analytics provides easy-to-use, off-the-shelf augmented intelligence and machine learning solutions built around its DataModeler platform, which optimizes multiple Key Performance Indicators simultaneously. Established in 2005 by Dr. Mark Kotanchek and Dr. Theresa Kotanchek, the company also offers consulting, project design, execution and training for nonlinear modeling of complex systems.

augmented intelligenceconsultingdesign of experimentsgenetic programmingmachine learningnonlinear modelingtraining

Glacian Technologies Inc. is a data center Physical AI software company. Its platform fuses physics-based models with advanced AI to reduce the power consumed by data center cooling systems, helping operators expand AI compute capacity without utility permits or major construction. The company's team is built on more than a decade of data-center cooling research supported by over $8 million in competitive research grants.

AI optimizationdigital twinsintegration with DCIM and cooling systemson-premise deploymentphysics-based modeling