intracellular trafficking

Celyra Therapeutics is a preclinical biotechnology company developing modular small-molecule scaffold systems for intracellular delivery. Its compounds act on the cell's own trafficking machinery to induce bulk uptake of large payloads and hold open the point at which cargo would otherwise be committed to degradation, then the effect reverses. The platform is cargo-agnostic, having enhanced cytosolic access for proteins, antibodies, oligonucleotides and nanoparticles.

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lipid nanoparticle engineeringmedicinal chemistryphosphoinositide biology