in vivo pharmacology

Biocytogen is a global provider of animal and cell model generation for preclinical research, offering gene-edited and humanized mouse models, cell lines, and integrated drug discovery services. Through its BioMice brand it supplies off-the-shelf and custom animal models, and it develops fully human antibody discovery platforms including the RenMice family (RenMab, RenLite, RenNano, RenTCRmimic, RenMice KO) based on its SUPCE gene-editing technology.

antibody discoverycolony management and breedingcryopreservationgene editinghumanized mouse modelsin vitro pharmacologyknockout/knockin mouse model generationnon-GLP toxicity studiesPK/PD studiesrederivation

EnquBio Inc is a San Diego-based drug R&D technology and service company (preclinical CRO) that advances pharmaceutical and biotechnology research through a comprehensive suite of drug discovery solutions. Located in San Diego's biotech hub, it operates state-of-the-art facilities led by an industry-recognized team, offering expertise in exploratory biology, high-throughput screening, SAR studies, in vitro and in vivo pharmacology, immunology-focused studies, biomarker discovery, and clinical sample analysis.

assay developmentbioanalysisbiomarker discoverycell line generationex vivo pharmacologygene expression analysisgenome editinghigh-content screeninghigh throughput screeningimmunoassayimmunophenotypingin vivo imagingiPSC platformnon-GLP toxicologyPK/PD analysisWestern blot

IRBM is a preclinical drug discovery organization based in Rome, Italy, conducting small molecule, peptide and antibody programs from target validation through to a preclinical candidate, either as a full integrated program or as a single capability for clients. Its scientists have contributed to three approved drugs and delivered more than thirty preclinical candidates to partners.

ADMEantibody phage displayassay developmentBioinformaticsbiophysical characterizationcompound managementcomputational chemistryDMPKfunctional genomicshigh-content screeninghigh throughput screeningmedicinal chemistrymRNA displayNMRpeptide chemistrypeptide phage displayprotein productionstructural biologysynthetic chemistry

Junipero Therapeutics is an early, funded gene therapeutics company based in Durham, North Carolina, working out of BioLabs Durham. It is building a new way to control gene expression using short synthetic molecules that guide a cell's own regulators to a target RNA, raising or lowering a single gene's output without DNA cuts or viral vectors.

computational biologymolecular and cell biologyoligonucleotide chemistry

K2bio provides integrated research solutions for biotech and pharmaceutical partners across every stage of discovery and development from its Houston-based facility. Services include in vitro research, in vivo pharmacology, analytical services, histology support, and access to an AAALAC- and OLAW-accredited vivarium, along with private lab spaces and lab benches outfitted with instrumentation and technical support.

analytical assayscontract vivariumefficacy modelshistologyIACUC protocolslab space leasingnecropsyPK/PDsurgical procedures