genomic and clinical dataset mining

Aperture Therapeutics is building a drug discovery platform that embraces the genetic diversity of patients and leverages mechanistic understanding of protective gene variants in the human population. Its platform identifies naturally occurring gene variants that protect against neurodegeneration, using machine learning to mine large-scale genomic and clinical datasets to prioritize gene variants with the strongest protective effects and rapidly design oligonucleotide therapeutics mimicking their effect. The company targets shared drivers of familial and

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drug discoverymachine learningoligonucleotide therapeutic design