custom synthesis

A1 BioChem Labs (ABCL), a subsidiary of Apitoria Pharma Private LTD, is a CRDMO offering comprehensive chemistry services to pharma, biotech, and academia. It operates advanced labs in Wilmington, NC, and Hyderabad, India, specializing in custom synthesis, medicinal chemistry, route scouting, analytical development, and commercial-scale manufacturing across FDA, EDQM, and PMDA approved sites.

analytical developmentchemical sourcingchiral analysisCMC supportcommercial-scale manufacturingDMPKflow chemistrygenotoxic impurity assessmenthigh-vacuum distillationhydrogenationmedicinal chemistrynitrosamine controlparticle-size distributionpolymorphismpowder processingprocess developmentprocess safetyroute scoutingsolid-state analysis

AAPharmaSyn is a US-based contract research organization (CRO) providing synthetic and medicinal chemistry services to pharmaceutical and biotechnology clients since 2006. Services include custom chemical synthesis, medicinal chemistry, custom lipid synthesis, stable isotope labeled compounds, process research and development, and project management support.

analytical supportasymmetric synthesischiral resolutionconjugation chemistryisotope labelinglipid synthesismedicinal chemistrymulti-step synthesisprocess chemistrypurification and characterizationroute scoutingscale-up/pilot synthesis

Leadership Leadership is one of our differentiating strengths at AAP. To efficiently execute your project, you require a strong, highly motivated team using the right, Learn More Resources The core of our team of chemists is composed of experienced chemists with MS degrees. The range in experience for our whole team is from years to recent, Learn More Services AAP was founded to offer customers needing custom synthesis a superb experience at an attractive price. We built our company around your needs. Speed, Learn More Our Growth Growth is never by mere chance; it is the result of forces working together... Learn More Services Get an early start on your process R&D. Send optimized procedures and practical routes with your tech packages. Who likes making reference standards? We do! The tougher the synthesis, the more we like it. Order key templates on a larger scale (and at a fraction.

organic synthesisprocess R&Dscale-up synthesis

Abiozen is a U.S.-based life sciences platform and B2B supplier of specialty chemicals, building blocks, intermediates, reference standards, and generic and GMP APIs for licensed pharmaceutical manufacturers, biotech, and research institutions worldwide. Founded in 2024, it operates as a technology-driven intermediary connecting suppliers, laboratories, and research teams, with orders routed through its Buffalo Grove, Illinois facility.

biostatistics and SAS programmingDMF filing supportFDA submission preparationGMP compliance consultingpharmacovigilanceprocess development and scale-upQC testing (HPLC, GC-MS, FT-IR, dissolution)supply chain and distribution

AccuStandard is a manufacturer of Certified Reference Materials and analytical reference standards, with a catalog of over 12,000 products and over 30,000 custom formulations. The company formulates organic, inorganic, petrochemical, and custom chemical standards for calibration of analytical instruments, method validation, and quality control. AccuStandard is accredited to ISO 17034, ISO/IEC 17025, and certified to ISO 9001, and marks its 40th anniversary in 2026.

chemical synthesis of high-purity research chemicalscustom standard manufacturingISO 17034 accreditationISO 9001 certificationISO/IEC 17025 accreditationreference material formulation

Affinity is a global CDMO based in Delaware, USA, serving the pharmaceutical, biotech and specialty chemical industries. Established by chemists, it provides a total solution from R&D to tonnage manufacturing with a team of over 150 chemical professionals, including 35 Ph.D.s.

asymmetric synthesisbiocatalytic reactionschlorinationcontinuous flow processescontract manufacturingenzymatic reactionsfluorinationheterocyclic synthesisheterogeneous/homogeneous catalysisorganometallic chemistryPEGylationpilot scale-upProcess Automationprocess developmenttonnage manufacturing

Alamanda Polymers specializes in the manufacturing of well-defined polyamino acids for research laboratories doing work in gene therapy, encapsulation, drug delivery, cell adhesion, and surface coating. The company provides metal-free biopolymers including homopolyamino acids and PEGylated polyamino acids, and was formed in 2007.

conjugationend-group functionalizationGPC coupled to light scatteringmaterials characterizationNMRpolymerization without metal catalysts

AmideBio discovers peptide therapeutics for metabolic disease, using in-silico design and its proprietary BioPure process to generate ultrapure peptides. Founded in 2009 to commercialize the BioPure platform, it sells peptides directly and offers custom synthesis services, and since 2016 has developed its own therapeutics targeting metabolic diseases, aiming to license drug candidates at or before the IND stage.

biological activity testingBioPure processin-silico peptide designpeptide synthesis

Ascent Chemicals is a U.S.-based specialty chemical manufacturer providing custom synthesis, custom (contract) manufacturing, and toll manufacturing, plus scalable production of specialty chemicals and intermediates. It combines core chemistries such as surfactants, polymerization, and esterification with flexible domestic manufacturing across three ISO 9001:2015 certified facilities in South Carolina, Tennessee, and Virginia.

amidationaminationbatch organic synthesisblendingbrominationcatalysiscontract manufacturingdispersionDistillationdryingemulsificationEncapsulationesterificationfiltrationflakinggrindingmillingpolymerizationtoll manufacturing

Avanti Research, a Croda brand, provides high-purity lipids and lipid research tools for scientific research. The company offers research products, custom synthesis, cGMP manufacturing, analytical services, lipidomics, formulations development, and extruder kits. Founded in 1967 in Richmond, Virginia by Dr. Walter A. Shaw, it moved to Pelham, Alabama in 1973, to Alabaster, Alabama in 1990, and was acquired by Croda International Plc. in 2020. The Avanti Research brand launched in 2024.

analytical servicescGMP manufacturingcontract manufacturing and packagingformulations developmentlipidomicsscale-up manufacturingsynthetic and analytical chemistry

Beantown Chemical, Inc. (BTC) is a privately held company founded in 2014 that manufactures and distributes a line of specialty chemicals, including organics, inorganics, and metals. Its corporate headquarters and main distribution center is in Hudson, NH. BTC offers over 10,000 products sold for research and development primarily to the pharmaceutical and chemical industries, government institutions, and academia, in pre-packaged catalog sizes and semi-bulk and bulk quantities, plus custom synthesis and special packaging services.

distributionmanufacturingspecial packaging

BLD Pharmatech is a research chemicals manufacturer and supplier serving pharmaceutical, biotech, CRO/CDMO, academic, material science, and electronics industries. It offers a catalog of 700,000+ compounds with 120,000+ in-stock items across warehouses in the US, Europe, and Asia, plus custom synthesis, process development, and scale-up manufacturing services. The company is certified to ISO 9001, ISO 14001, and ISO 45001.

chiral separationchromatography (HPLC, GC, Chiral HPLC & GC, TLC)ICP-MS trace metal analysismass spectroscopy (LC-MS, GC-MS)method developmentNMR (HNMR, CNMR, QNMR)physiochemical testingpreparative chromatography (Prep-HPLC, Prep-SFC, Prep-NPLC)process developmentscale-up manufacturing

Blue Line Corporation is a developer, manufacturer and supplier of inorganic chemicals, specializing in rare earth and transition metal products. The company manufactures pure metal salts in powder or solution chemistry, and specializes in rare earth, zirconium compounds and sol-gel technology. It has been manufacturing inorganic salts since 2001 and serves clients ranging from start-ups to international corporations.

chemical process developmentdrying/crystallizationgrinding and screen separationhazmat packaginglaser diffraction particle size analysisliquid storageparticle sizingpilotingreactions and digestionsResearch and Developmenttoll manufacturing

CalChem Synthesis is a US-based Contract Research Organization (CRO) providing chemistry services to biotech and pharmaceutical companies, research institutions, and cosmetic and nutraceutical companies. Founded by Dr. Jalal Haddad, the company offers custom synthesis of organic molecules, process research and development, scale-up, and sourcing and procurement services. Its chemistry activities are directed by Ph.D. level organic chemists with combined 35 years of experience.

analytical method developmentmedicinal chemistryprocess research and developmentscale upsourcing and procurementsynthesis of building blocks, intermediates, APIs, and drug conjugatessynthesis of process impurities, metabolites, and reference compoundssynthesis of toxicology batchestechnology transfer reports

Cambridge Polymer Group (CPG) provides contract research and analytical testing services in materials science, with decades of cross-industry experience. The company helps clients select materials, develop designs, optimize manufacturing processes, and mitigate regulatory risks, serving industries including healthcare, robotics, supply chain, and sustainability. Its GLP-compliant and ISO-accredited laboratory offers routine and custom testing in accordance with ASTM, ISO, USP, and other standards.

analytical testingbiocompatibility testingdeformulationextractables and leachables testingfailure analysisGLP testingmaterial characterizationmechanical testingmethod development and validationregulatory testingrheological analysisthermal analysis

CellMosaic, Inc. is a bioconjugation company founded in 2008 and based in Woburn, Massachusetts. It develops proprietary AqueaTether® (AqT®) technologies and provides custom bioconjugation services, bioconjugate drug development and manufacturing, diagnostic conjugate development, and bioanalytical services including HPLC analysis, purification, and bioassays. It also sells bioconjugation kits and reagents for antibody, protein, peptide, oligonucleotide, and small molecule labeling.

ADC development and manufacturingantibody fragmentationantibody labelingbioassay servicesbioconjugate drug development and manufacturingbioconjugationbiotinylationcrosslinkingfluorescent dye labelingHPLC analysispurification

Chem-Master International, Inc. is a research, development, and manufacturing company founded in 1994 that specializes in contract projects, providing custom chemical synthesis, process development, and chemical research services to pharmaceutical companies, biotechnology organizations, drug discovery groups, and academic institutions in the U.S. and Europe.

analytical methods development and validationcGMP synthesischemical researchcontract synthesisFT-IRGCHPLCLC/MSNMRprocess chemistryprocess developmentroute scouting and selectionscale up

ChemoGenics BioPharma is a drug discovery research and service organization providing preclinical drug discovery services to pharmaceutical, biotechnology, academic and government institutions globally. It has facilities in the Research Triangle Park Area in the United States and serves clients in the U.S. and Europe. Its core team has 10+ years of experience in preclinical drug discovery, with strengths in medicinal chemistry, cheminformatics, bioinformatics, ADMET and in vivo pharmacology in metabolic disease, oncology and inflammation.

analytical chemistrybioinformaticscGMP manufacturing of APIcheminformaticscloningcomputer-aided drug designin vitro ADMEIn vivo PK/PDmedicinal chemistrymolecular modelingProcess optimization and scale upRecombinant protein synthesis

ChemUniverse, Inc. is a specialty chemical supplier serving research and industrial buyers with 93,000+ products, offering organic, inorganic, polymer, life sciences and specialty chemicals from milligram quantities to bulk orders. The company provides custom synthesis, hard-to-find sourcing, bulk orders and blanket POs, and hazmat and international shipping, with responsive quoting and customer support.

bulk orders and blanket POshard-to-find sourcinghazmat and international shipping

ChiroBlock is a synthetic chemistry and contract research company based in Wolfen, Germany, specializing in custom synthesis of complex, commercially unavailable molecules. Since 1999 it has provided services from first-time synthesis to scalable production (mg to kg), including route scouting, process development, and reliable supply of high-purity compounds under ISO 9001 quality management.

catalysischromatographyflow chemistryGC-MShigh pressure/low temperature reactionsHPLCinert gas/organometallic chemistryIRmulti-step organic synthesisNMRphotochemistryprocess developmentRoute optimizationroute scoutingscale upSEC

Copperhead Chemical Company® Inc. is a manufacturer of pharmaceutical-grade nitroglycerin (glyceryl trinitrate) and diluted nitroglycerin mixtures for cardiac therapy, energetic materials for propellants, fuel additives and munitions, and plant-based preservative and cosmetic ingredients. Its FDA-registered Tamaqua, PA facility operates under GMP and Process Safety Management, and the company offers custom manufacturing and custom synthesis.

blendingcustom analytical workCustom ManufacturingGMP manufacturinglab-scale custom synthesisnitration of glycol estersscreening and testingTechnical Support

CortecNet is a Stable Isotopes-driven company, devoted to identifying, developing and marketing innovative products in the fields of NMR, MS, MRI, and PET. It supplies stable isotopes, deuterated solvents, NMR consumables, isotopic gases and metals, and offers services including gas packaging, labeled protein expression, custom synthesis, and solid-state NMR services.

centrifuge methodD2O recoverydistillation or chemical methodelectromagnetic methodgas packagingH2O18 recoverylabeled protein expressionphotochemical methodsolid-state NMR services

Dipharma Inc. is a chemistry Contract Development and Manufacturing Organization (CDMO) based in Kalamazoo, Michigan, USA, whose scientists average 15 years' experience in pharmaceutical development from lead optimization through process development for clinical development. Its cGMP Kilolab and QC Laboratories manage supply for clinical Phase 1 and early Phase 2 deliveries, and it offers CRO services for synthetic projects.

analytical developmentcGMP manufacturingchromatographyDSCGChigh-pressure hydrogenationHPLCLC/MSNMR spectroscopyprocess impurity synthesisprocess route developmentQC laboratoriesXRPD

Enamine is a chemistry research organization and CRO that has been accumulating chemical knowledge and experience since 1991. It provides integrated drug discovery services, compound library synthesis, custom synthesis, FTE chemistry support, CADD, biology, and hit follow-up support, backed by over 650 chemists and the world's largest collection of building blocks.

1H NMRADMET profilingasymmetric synthesiselectrochemistryfluorination with SF4free energy perturbationhigh-pressure hydrogenationHTSLCMS quality controllibrary synthesismolecular dockingmolecular dynamicsparallel synthesisphotochemistry in flowQSAR modelingreversed-phase preparative HPLC purificationvirtual screening