conformational landscape mapping

AlmaDyne is an AI-powered drug discovery company whose mission is to unlock undruggable targets by mapping the full conformational landscape of disease-relevant proteins in their native biological environment. It models the full dynamic range of proteins in native membrane or cytoplasmic environments to reveal transient conformations and hidden binding pockets, and validates AI-designed candidates in vitro and in vivo with Columbia and King's College London.

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AI protein dynamics modelingin vitro validationin vivo validationstructure-based drug design