computational drug design

Adipothera is a drug discovery company developing AI-driven therapies targeting the stromal microenvironment for diseases driven by fibrosis and inflammation. Its pipeline generates first-in-class drug candidates that are computationally guided, assay-proven, and clinically motivated. Lead candidates include AT-001 (topical) for radiation injury and lymphedema, and AT-002 (oral) for Fibrodysplasia Ossificans Progressiva (FOP) and Heterotopic Ossification (HO).

AI-driven drug discoveryin-silico triagePK/PD modelingpreclinical assaystopical and oral drug formulation

Chemotargets is a Barcelona-based company that collects and learns from biomedical data to advance drug discovery and development. It offers the SafetySuite collection of data, signals and analytics products (SafetyOne, SafetySignals, SafetyStrata, SafetyVista) and CLARITY, a software platform for predictive off-target pharmacology and safety of small molecules. It also provides drug safety, repurposing and discovery services, and has a multidisciplinary team of more than 30 computational biologists, chemists, data scientists and software developers.

ADME predictionde novo design and scaffold hoppingdrug repurposingmachine learning-aided drug designmolecular dynamics simulationspharmacovigilance analyticspredictive pharmacology and safetyvirtual fragment-based screening

Early Charm is a vertically integrated company that takes science from research institution licenses to commercial production, with R&D and manufacturing under one roof in Baltimore, Maryland. It serves both defense and commercial markets, developing dual-use products across advanced materials, bioengineering and biodefense, and sensors and analytics. The company reports 90 products in its pipeline and 11 fully commercial products, and is an SBIR/STTR awardee that is DCAA-compliant and SAM + CAGE registered.

3D bioprinting3D printingbiomanufacturingcastingcoatingcustom material formulationData Analyticselectrospinningoptical systemspoint-of-care diagnosticsprecision prototypingsonar-based monitoringspectroscopysurface engineering